AI x Clinical Benchmarking

A leading AI lab's foundation model was failing on medically complex cases and multi-turn conversations. We designed clinical evaluation frameworks with specialist physicians, identified performance gaps across pediatrics, oncology, and nuclear medicine, and delivered targeted datasets with human-in-the-loop feedback.
Problem
Foundation models pass medical exams but fail on complex clinical conversations—without clear metrics to measure what's actually broken.
Approach
We designed physician-led evaluation frameworks that stress-test models on real clinical scenarios, identified specific failure modes across specialties, then built targeted datasets with expert validation to systematically address each gap.
Industry
AI Labs
Services
Specialized Evaluation Framework & Dataset Development
Result
35%
improvement in rubric scores across medical accuracy, and emergency referral protocols.

A major AI lab was preparing to launch healthcare products but lacked confidence in clinical performance. Their foundation model passed standard medical benchmarks but failed unpredictably on:

  • Medically complex, multi-turn patient conversations
  • Edge cases across specialized domains (pediatrics, oncology, nuclear medicine)
  • Nuanced clinical judgment requiring empathy and appropriate emergency referrals

Without quantifiable metrics for open-ended medical responses and clear visibility into model vulnerabilities, they couldn't deploy with confidence.

Our Approach:

01 - Clinical Benchmark Design: Collaborated with 10-20 specialist physicians to create multi-turn conversation scenarios reflecting real clinical complexity. Developed detailed rubrics measuring medical accuracy, clinical empathy, and appropriate escalation protocols.

02 - Systematic Gap Analysis: Tested the foundation model against clinical ground truth. Categorized failure modes by specialty, conversation depth, and error type. Identified specific weaknesses invisible to standard benchmarks.

03 - Targeted Dataset Development: Built custom training datasets focused on identified failure modes. Each sample included prompt, model response, expert-validated "golden" response, and per-turn scoring rubric.

04 - Human-in-the-Loop Refinement: Physician network provided iterative feedback on model outputs. Continuous validation ensured improvements transferred to real clinical scenarios, not just benchmark performance.

Key Takeaway:

"Standard medical benchmarks test what's easy to measure, not what matters clinically. We designed evaluation frameworks that revealed real vulnerabilities—then built the infrastructure to address them systematically."

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